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Sandrine Delbosc Selected Research

N- ((5- (methanesulfonyl)pyridin- 2- yl)methyl)- 6- methyl- 5- (1- methyl- 1H- pyrazol- 5- yl)- 2- oxo- 1- (3- (trifluoromethyl)phenyl)- 1,2- dihydropyridine- 3- carboxamide

2/2016Elastase inhibitor AZD9668 treatment prevented progression of experimental abdominal aortic aneurysms.

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Sandrine Delbosc Research Topics

Disease

9Thrombosis (Thrombus)
01/2018 - 04/2011
7Hypertension (High Blood Pressure)
07/2008 - 08/2002
6Abdominal Aortic Aneurysm
04/2016 - 10/2010
5Atherosclerosis
01/2017 - 10/2002
4Stroke (Strokes)
12/2020 - 07/2010
4Hemorrhage
08/2018 - 02/2005
4Aneurysm (Aneurysms)
02/2016 - 04/2011
4Insulin Resistance
01/2008 - 09/2004
4Cardiomegaly (Heart Hypertrophy)
09/2007 - 05/2003
3Infarction (Infarctions)
12/2020 - 07/2010
3Inflammation (Inflammations)
12/2020 - 01/2005
2Ischemic Stroke
12/2020 - 01/2018
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2020 - 01/2017
2Sepsis (Septicemia)
06/2019 - 07/2004
2Acute Coronary Syndrome
01/2018 - 01/2012
2Atherosclerotic Plaque (Atheroma)
01/2017 - 01/2012
2Rupture
11/2013 - 03/2013
2Endocarditis
05/2013 - 01/2012
2Aortic Aneurysm (Aneurysm, Aortic)
03/2013 - 10/2010
2Embolic Stroke
03/2013 - 07/2010
2Type 2 Diabetes Mellitus (MODY)
10/2012 - 01/2008
2Albuminuria
09/2007 - 05/2003
1Septic Shock (Toxic Shock Syndrome)
06/2019
1Reperfusion Injury
08/2018
1Ischemia
08/2018
1Aortic Dissection
01/2018
1Hematoma
01/2018
1Hypercholesterolemia
01/2017
1Tertiary Lymphoid Structures
01/2014
1Bacteremia
03/2013
1Stable Angina
01/2012
1Coronary Artery Disease (Coronary Atherosclerosis)
01/2012

Drug/Important Bio-Agent (IBA)

7HDL LipoproteinsIBA
12/2020 - 07/2010
7Reactive Oxygen Species (Oxygen Radicals)IBA
11/2013 - 10/2002
5Proteins (Proteins, Gene)FDA Link
12/2020 - 01/2005
4Matrix Metalloproteinases (MMPs)IBA
12/2020 - 05/2008
4Biomarkers (Surrogate Marker)IBA
12/2020 - 07/2008
4Phenobarbital (Luminal)FDA Link
02/2016 - 04/2011
4AntioxidantsIBA
11/2013 - 08/2002
3Tissue Plasminogen Activator (Alteplase)FDA Link
01/2020 - 03/2013
3Pancreatic Elastase (Elastase)IBA
02/2016 - 01/2012
3Peptide Hydrolases (Proteases)FDA Link
05/2013 - 01/2012
3Simvastatin (Zocor)FDA LinkGeneric
09/2007 - 08/2002
3Angiotensin IIIBA
09/2007 - 08/2002
3NADPH Oxidases (NAD(P)H oxidase)IBA
03/2005 - 01/2005
3FructoseIBA
03/2005 - 09/2004
3Superoxides (Superoxide)IBA
02/2005 - 10/2002
2Neuroprotective AgentsIBA
12/2020 - 07/2010
2Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
12/2020 - 07/2010
2ChemokinesIBA
12/2020 - 01/2014
2Cell-Free Nucleic AcidsIBA
12/2020 - 04/2011
2DNA (Deoxyribonucleic Acid)IBA
08/2018 - 01/2018
2Peptides (Polypeptides)IBA
08/2018 - 01/2018
2ApolipoproteinsIBA
01/2018 - 02/2015
2Hemoglobins (Hemoglobin)IBA
01/2017 - 10/2012
2LipidsIBA
10/2012 - 01/2005
2Insulin (Novolin)FDA Link
01/2008 - 09/2004
2acetovanillone (apocynin)IBA
09/2007 - 02/2005
2PolyphenolsIBA
01/2005 - 09/2004
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
10/2002 - 08/2002
1high density lipoprotein receptorsIBA
12/2020
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
12/2020
1OsteopontinIBA
12/2020
1ResistinIBA
12/2020
1AdiponectinIBA
12/2020
1Antithrombin IIIIBA
12/2020
1Metalloproteases (Metalloproteinases)IBA
12/2020
1Pregnancy-Associated alpha 2-Macroglobulins (alpha 2 Macroglobulin)IBA
12/2020
1Neuropilin-1IBA
12/2020
1Cystatin CIBA
12/2020
1Complement System Proteins (Complement)IBA
12/2020
1CD40 Ligand (CD40L)IBA
12/2020
1cathepsin SIBA
12/2020
1Platelet Endothelial Cell Adhesion Molecule-1IBA
12/2020
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
12/2020
1Kallikreins (Kallikrein)IBA
12/2020
1Complementary DNA (cDNA)IBA
12/2020
1LigandsIBA
12/2020
1Plasminogen Activator Inhibitor 1IBA
12/2020
1Pre-beta High-Density LipoproteinsIBA
01/2020
1Lipoproteins (Lipoprotein)IBA
06/2019
1AngiotensinsIBA
01/2018
1Apolipoproteins E (ApoE)IBA
01/2018
1CollagenIBA
01/2018
1Glycophorins (Glycophorin C)IBA
01/2017
1Streptozocin (Streptozotocin)FDA Link
01/2017
1IronIBA
01/2017
1N- ((5- (methanesulfonyl)pyridin- 2- yl)methyl)- 6- methyl- 5- (1- methyl- 1H- pyrazol- 5- yl)- 2- oxo- 1- (3- (trifluoromethyl)phenyl)- 1,2- dihydropyridine- 3- carboxamideIBA
02/2016
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
07/2013
1ElastinIBA
07/2013
1P-SelectinIBA
03/2013
1fucoidanIBA
03/2013
1Serine Proteases (Serine Protease)IBA
10/2012
1Enzyme Precursors (Zymogens)IBA
10/2012
1CathepsinsIBA
10/2012
1Leukocyte Elastase (Neutrophil Elastase)IBA
01/2012

Therapy/Procedure

7Therapeutics
12/2020 - 02/2005
1Injections
04/2016
1Aftercare (After-Treatment)
07/2013
1Intravenous Injections
03/2013